||About 170 are chronically infected with hepatitis C (HCV) around the world and run the risk of developing liver cancer. In
Pakistan, approximate 5% of the population are chronic carriers , affecting both genders from all age groups and social classes
though certain groups suffer more. It is spread through contact with infected blood. While in developed countries this is
through invasive drug use, in developing countries it through medical equipment. Determinants, play a vital role in HCV transmission
and spread and are often intertwined. However, the factors much like the disease are not well understood and not contextual.
As a result, there is a need to understand these factors for formulate evidence-based interventions in an efficient and equitable
manner. The interventions thus far have been combined with HIV and hepatitis B strategies, thus tackling multiple diseases
at once. But interventions must be more holistic and include involvement from other sectors, e.g. urban affairs and housing
to make a dent in prevalence. Furthermore, with populations becoming more mobile, so has the virus. In the wake of the recent
global response to viral hepatitis and recent WHO initiatives, this is the perfect time to use the momentum, develop a roadmap
for Pakistan and mobilize resources and efforts. This thesis attempts to provide an understanding about the determinants and
formulate a road map for Pakistan.